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Catch up fat phenotype

Quickly and easily regaining lost fat is known as “catch-up fat” or a thrifty metabolism. This is associated with obesity, type 2 diabetes and cardiovascular diseases, and characterized by high insulin levels. Mechanisms involved include suppressed thermogenesis, de novo lipogenesis…

Sucrose, visceral fat and testosterone

Sucrose (table sugar) fed rats had lower testoserone levels, higher blood pressure and more visceral fat than controls. Castrating the animals reversed the fat accumulation, hypertension and lowered their triglycerides. Testosterone injections reveresed these improvements while estrogen did not. Obviosly…

Weight loss plateaus

Weight loss plateaus occur after an average weight loss of around 11% of body weight. At this point, the resting metabolic rate is significantly lower and hunger is significantly higher. Depression may also be present. It may be appropriate to…

Low glycemic diets and weight loss

It is reasonably well established that reducing the amount of carbohydrate or lowering the glycemic index of the carbohydrates eaten both improve the rate of weight loss and cardiovascular risk factors. Both of these approaches lowers the total glycemic load…